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Arezoo Monfared, Mohammad Taghi Moghadamnia, Samad Karkhah, Saman Maroufizadeh, Mohammad Asadian Rad, Jalal Kheirkhah, Fatemeh Jafaraghayee,
Volume 9, Issue 4 (12-2021)
Abstract

Background and Objective: In the current COVID-19 pandemic, disease diagnosis is essential for optimal management and timely isolation of infected cases in order to prevent further spread. The aim of this study is to assess of predictors of mortality among COVID-19 patients.
Material and Methods: In a retrospective study, 522 COVID-19 patients were enrolled in Razi hospital, Guilan Province, Iran. This hospital was the main center for the treatment of COVID-19 patients in Guilan province. Data gathering was performed by census sampling from March to August 2020. Simple and Multiple logistic regression analysis was applied to assess the relationships of clinical and demographic characteristics with in-hospital mortality.
Results: Multiple logistic regression showed that older age (aOR=1.04, 95%CI: 1.02 to 1.06, P<0.001), decreased O2 saturation (aOR=0.89, 95%CI: 0.86 to 0.92, P<0.001), having a dysrhythmia (aOR=2.97, 95%CI: 1.46 to 6.05, P=0.003), symptoms associated with heart failure (aOR=0.43, 95%CI: 0.18 to 0.99, P=0.048), and mixed drug antiviruses (aOR=2.44, 95%CI: 1.22 to 4.90, P=0.012) were mortality predictor variables among COVID-19 patients.
Conclusion: Therefore, special attention should be paid to the factors influencing the mortality of COVID-19 patients. It is recommended that older patients, dysrhythmia, and symptoms associated with heart failure be treated with extreme caution.

Vahid Monfared , Leila Sheikhi , Mohtaram Hashemi , Fatemeh Kiani , Reyhane Javid , Mahya Nikoumanesh , Yegane Ghelichi , Alireza Hatami , Motahareh Hasani ,
Volume 13, Issue 4 (11-2025)
Abstract

Background: This systematic review and meta-analysis evaluated the effects of the DASH diet on blood pressure in overweight or obese adults with hypertension.
Methods: A comprehensive literature search was conducted in online databases, including SCOPUS, Medline, and Web of Science, up to 1 February 2024.
Results: This meta-analysis incorporated a comprehensive collection of 21 studies. The findings indicated that the DASH diet had a notable impact on decreasing systolic blood pressure (SBP), as demonstrated by a weighted mean difference (WMD) of -4.75 mmHg (95% confidence interval (CI): -6.23, -3.28; P < 0.001). Additionally, the DASH diet was found to have a significant influence on reducing diastolic blood pressure (DBP) [WMD of -4.17 mmHg (95% CI: -4.34, -4.00; P < 0.001)]. Subgroup analysis revealed that the results remained significant when age was ≥50 years, in females, among ethnic groups from Europe, Asia, and America, as well as in groups classified as obese individuals.
Conclusion: The DASH diet has conclusive effects on blood pressure, especially in obese individuals. The DASH diet could be considered an important dietary strategy for the management of hypertension in obese and overweight adults.


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